Online Internship Courses

Duration: 10 Days
Mode: Online
Certification Provided

In - Silico Vaccine Designing


  • Introduction to reverse vaccinology
  • Workflow of In-Silico Vaccine designing
  • Protein sequence retrieval
  • Antigenicity prediction
  • Allergenicity prediction
  • B-Cell and T-Cell Epitopes prediction
  • Multi epitopes vaccine construct
  • Vaccine construct secondary structure prediction
  • Vaccine construct physio-chemical properties
  • Population coverage analysis
  • Antigen-antibody docking using Online docking tools
  • Molecular Visualization of docked complex using softwares (UCSF Chimera)
  • Vaccine immune simulation study using online tools

In - Silico Drug Designing


  • Introduction to Bioinformatics
  • Ligand Designing
  • ADMET and Drug-likeness Prediction
  • Drug Target Selection by Proteomics approach
  • Drug Target Structure Optimization
  • BMolecular Docking by AutoDock Vina
  • IC50 Calculation by Cygwin software
  • Visualization of Protein-Ligand Interaction

Next Generation of Sequencing Data


  • Basics of Network Pharmacology
  • Protein Target Selection by Network Pharmacology
  • Drug Target Retrieval
  • PPI Network Construction
  • Identification of Hub Genes
  • Gene Ontology Prediction
  • KEGG Pathway Analysis
  • Inhibitor Designing
  • ADMET Analysis and Screening
  • Molecular Docking using AutoDock Vina
  • Protein-Ligand Interaction Analysis

Network Pharmacology


  • Basics of Network Pharmacology
  • Drug Targets Identification
  • Identification of Hub Genes
  • Protein-Protein Interaction Analysis
  • Gene Ontology Prediction
  • Gene Enrichment and Pathway Analysis
  • Compound-Target Network Construction
  • Molecular Docking by AutoDock (Cygwin)
  • Inhibition Constant (IC50) Calculation
  • Molecular Visualization by Discovery Studio

Pharmacophore Modelling


  • Pharmacophore modelling in Drug Discovery
  • How to do Pharmacophore Modelling
  • Virtual Screening of Bioactive Compounds by Drug- likeness
  • Lead Candidate selection by ADMET Properties
  • Molecular Docking by AutoDock 4.2
  • Inhibition Constant Calculation using Cygwin
  • Protein-Ligand Interaction Analysis using Bio Discovery Studio and PLIP Tool

Advanced Proteomics


  • Data Retrieval from Biological Databases
  • Identification of Unique Proteins from Pathogen
  • Identification of Essential Proteins from Pathogen
  • Identification of Druggable Proteins
  • 3D Modelling
  • Structure Validation
  • Protein-Ligand Docking by AutoDock
  • Visualization of Protein-Ligand Complex

Cancer Genomics and Proteomics


  • Introduction to Cancer Biology
  • Exploration of Various Cancer Genomics Databases
  • Visualization of Cancer Genomic Data
  • Catalogue of Somatic Mutations in Cancer
  • Identification of Somatic Mutations in Cancer
  • Tumor and Normal Sample pairs using Galaxy Platform
  • Prediction of Somatic DNA Mutation with Genome
  • Prediction of Druggability Cavity Pockets
  • Screening of Kinase Inhibitors from Medicinal Plants
  • Molecular Docking using AutoDock Vina
  • Molecular Visualization using Bio Discovery Studio 2021

Microbial Proteomics


  • Basics of microbial proteomics
  • Exploration of biological databases
  • Target selection
  • Data retrieval
  • Identification of Unique Proteomic Profile
  • Data mining using KEGG Pathway
  • Identification of druggability proteins
  • Protein modelling
  • Structure optimization and validation
  • Ligand designing
  • Screening of Ligands
  • ADMET and Druglikeness Predictions
  • Molecular Docking using AutoDock Vina
  • Visualization of docked complex using Discovery studio 2024

In-Silico Mutational Analysis


  • Data Retrieval from Biological Databases
  • Uploading data to galaxy server
  • Raw data QC and interpretation
  • Reference based alignment
  • De novo genome assembly
  • Genome finishing
  • Genome annotation
  • Assembly statistics and genome mapping

Whole Genome Sequencing Data Analysis


  • Basics of Whole Genome Sequencing
  • Data Uploading to Galaxy Server
  • Reference Genome based Alignment and Genome Mapping
  • De novo assembly
  • Genome Finishing
  • Genome Assembly Statistics
  • Genome Map Construction

Flow Cytometry


  • Basics of Flow Cytometry
  • Applications of Flow Cytometry
  • Know Your Cytometer (KYC)
  • Machine Setup, QC, Voltage/Gain Settings
  • Sample Preparation, Experimental Designing. Controls
  • Panel Designing, Spectral Overlap & Compensation
  • Cell Sorting
  • Advances in Flow Cytometry (Spectral)
  • Data Analysis and Presentation (Basic & High Dimensional)
  • Live Demonstration of Instrument Setup & Data Acquisition
  • Q & A, Troubleshooting, Self Assessment

Biostatistics


  • Introduction to the interface
  • Data type
  • Dataset - Variables
  • Data Recode
  • Sort Cases
  • Import data from MS Excel and Text File
  • Graphs and Charts Making
  • Cross tabulation
  • Correlation analysis
  • Multiple and Logistic regression
  • Hypothesis Testings
  • T-test
  • Chi-square Test
  • F-Test
  • One Way-ANOVA and Two Way-ANOVA

AI Tools for Research


  • AI Tools for Finding Research Ideas
  • AI Tools for collecting resources
  • AI Tools for Reading & Reviewing Research Papers
  • AI Tools for Editing & Proofreading Research Papers
  • AI Tools for Citing Sources
  • AI Tools for Detecting Plagiarism and AI Content
  • AI Tools for reducing Plagiarism
  • AI Tools for writing SOP
  • AI Tools for Data Analysis
  • AI Tools for Coding
  • AI Tools for Plotting Graph